Senior Director, Targets and Mechanisms Solutions

About this role

Why Patients Need You Technology impacts everything we do. Pfizer’s digital and ‘data first’ strategy focuses on implementing impactful and innovative technology solutions across all functions from research to manufacturing. Whether you are digitizing drug discovery and development, identifying solutions, or making our work easier and faster, you will be making a difference to countless lives.

Pfizer’s purpose, breakthroughs that change patients’ lives, is rooted in being a science driven and patient focused company. Digital, data, and technology are central to driving innovation at Pfizer.

The Senior Director, Targets and Mechanisms Solutions, as part of the R&D Creation Center’s Discovery, Pre-Clinical, and Translational Solutions Team, will lead strategic direction, product management, and AI-driven innovation for Pfizer’s Targets and Mechanisms platforms and systems. You will oversee a global team responsible for delivering scalable, sustainable, and science-centric solutions that power research execution across Pfizer and any in-scope external partners. As a senior leader, you will drive strategic planning for your organizations platforms and systems, integrating advanced technologies including AI, data pipelines, and predictive analytics to enhance efficiency and decision-making. The ideal candidate has experience at the intersection of research and digital technologies including enterprise-level systems, with passion to make a difference at scale, a commitment to growing others, and the curiosity and courage to experiment and innovate in the ever changing digital and healthcare landscape.

ROLE RESPONSIBILITIES Targets and Mechanisms Solutions Enablement In collaboration with Digital & Technology peers and Pfizer R&D business stakeholder team members, the Senior Director, Targets and Mechanisms Solutions, will deliver technical services including ecosystem architecture, quality, analytics, and data management to design, build, and deliver innovative, cost effective, and sustainable solutions to identify biological targets for therapeutic modulation.  The work you and your team will do will enable: • Pfizer’s Research Units (RUs): Oncology, Vaccines, Internal Medicine, Inflammation & Immunology (I&I), and Integrative Biology (IB)

• Understanding disease pathophysiology

• Target Identification, qualification, and selection

• Leveraging large-scale omics data quantitatively to generate therapeutic hypotheses

• Mining scientific literature and proprietary data

• Supporting reverse-translational efforts from clinical data

• Shape preclinical model strategy to ensure human relevance and de-risk efficacy and safety

• Build translational biomarker frameworks that link preclinical insights to early clinical decisions

• Prioritize indications and expansion opportunities using genetics, multi-omics, and competitive intelligence

  Vision and Strategy • Defines and owns the vision and strategy for digital Targets and Mechanisms Solutions capabilities, with an additional focus on AI innovation and the development of product capability roadmaps to support Pfizer's research strategy with cutting-edge digital technologies.

• Defines and owns the Ecosystem Architecture architecting a modular, interoperable digital ecosystem that integrates scientific data products, metadata frameworks, and platform interoperability across systems and enables AI technologies across the value chain.

• Anticipates technology trends supporting business capabilities in area of remit with an additional focus on AI to prioritize investments that provide a competitive advantage and align with new technology and business practices within the research domain.

• Collaborates across Digital & Technology and business areas to select, pilot, and scale emerging innovations and technologies that drive Pfizer's research strategy forward.

• Continuously identify external solutions and have an awareness of best practices from competitors.  

• Participation / Leading of pre-competitive consortia as applicable.

Strategic Leadership • Establishes and matures a strategic product and platform operating model to drive scalable innovation.

• Operationalizes emerging technologies through robust governance frameworks to ensure alignment with business objectives, regulatory, and compliance requirements (as required).

• As required, designs and leads a strategic vendor framework to manage high-impact partnerships with critical vendors, ensuring measurable quality delivery and support.

• Launches and scales AI program(s) to embed AI into core workflows and to build process mining capabilities to uncover operational inefficiencies and inform continuous improvement strategies.

Program Delivery Leadership • Accountable for global Digital & Technology program delivery, overseeing technology implementation across all supporting areas, with responsibility for business case, supporting key performance metrics and financial management for highly complex continuous delivery activities.

• Responsibilities include delivery of global, enterprise, software-as-a-service solutions, and as needed custom software development solutions.

• Oversee the delivery management and engineering leadership of your portfolio of digital programs and projects.

• Demonstrated command of software development methodologies and solution delivery processes and practices (Agile, Waterfall, DevSecOps) with strong leadership and accountability for business outcomes.

• Financial responsibilities include accurate financial and resource forecasting, meticulous cost and budget management, strategic sourcing with robust supplier partnerships, and monitoring earned value to ensure project and business success.

• Ensure GxP solutions are continuously audit- and inspection-ready by maintaining compliance with regulatory requirements, proactively identifying and addressing gaps, and supporting successful internal and external audits and inspections.

Team Leadership

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