Director, Clinical Imaging, Translational Sciences-Immunology

About this role

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com

As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world.  We provide an inclusive work environment where each person is considered as an individual.  At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Job Function: Discovery & Pre-Clinical/Clinical Development

Job Sub Function: Translational Discovery & Development Biomarkers

Job Category: Scientific/Technology

All Job Posting Locations: Spring House, Pennsylvania, United States of America

Job Description: About Innovative Medicine Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way. Learn more at https://www.jnj.com/innovative-medicine

About Immunology Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Our Immunology team leads in the development of transformational medicines for immunological disorders and illnesses. You can influence where medicine is going by restoring health to millions of people living with immune diseases.   Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

We are searching for the best talent for a Director, Clinical Imaging-Translational Science- Immunology, to be in Spring House, PA or Cambridge, MA.   The Director, Clinical Imaging will provide strategic and scientific leadership for the development, validation, and delivery of imaging-derived endpoints to enable high-impact decision-making across the Immunology portfolio, with a primary focus on Gastrointestinal (GI) diseases. The role is US-based (Spring House, PA or Cambridge) and sits within the Translational Science organization, operating in a highly matrixed environment across Immunology Disease Area Strategy, Clinical Development, Data Sciences, Regulatory, and operational functions. This position is intentionally scoped and graded to ensure imaging and digital capabilities are positioned as strategic assets for Immunology, driving endpoint innovation for precision medicine from early to late phase. The Director will balance innovation, platform building, and technical delivery, ensuring that advanced measurement approaches are translated into fit-for-purpose, scalable solutions that support portfolio objectives.

Key Responsibilities:

Scientific & Strategic Technology Leadership • Lead the GI-focused imaging measurement strategy across Immunology assets, spanning early through late-phase clinical development. • Shape endpoint strategies integrating imaging measurements to support mechanistic understanding, proof-of-concept, and decision-enabling outcomes including regulatory. • Partner with Disease Area Strategy and Translational Science leaders to ensure alignment with portfolio priorities and clinical development plans. • Contribute to investment cases, governance discussions, and portfolio reviews, articulating value, readiness, and risk.

Clinical Trial Delivery & Execution • Provide scientific oversight and accountability for imaging endpoints across early- and late-phase clinical trials. • Ensure methods have an operationally delivery model to scale. • Partner with clinical and operational partners across the organization, Data Sciences, and external vendors/CROs to ensure on-time, high-quality delivery. • Support regulatory interactions related to imaging endpoints.

Innovation, AI & Capability Building • Identify and advance next-generation imaging technologies with clear trajectories to GI pipeline impact from novel molecular methods through to AI-based structural endpoints. • Lead the integration of AI-enabled analytics for imaging and digital endpoints, in close partnership with the Data Science organization. • Co-develop AI-based solutions (e.g. automated image analysis, quantitative feature extraction, digital signal interpretation) to improve scalability, reproducibility, and decision-making in high impact areas. • Build and sustain external collaborations with academia, technology partners, and pre-competitive consortia. • Translate emerging methods into pragmatic clinical solutions balancing innovation with feasibility and timelines.

Matrix Leadership & Influence • Partner closely with the Imaging and Digital Health team colleagues to drive innovation and delivery across disease areas. • Operate effectively in a complex, global matrix environment and influence to guide strategy. • Serve as a trusted scientific advisor to project teams, DAS leadership, and senior stakeholders. • Communicate complex technical concepts with clarity and impact to diverse audiences. • Mentor and develop scientists and matrix partners, contributing to a culture of scientific excellence and accountability.

  Qualifications & Experience Required • PhD or MD, or equivalent advanced degree in a relevant scientific or clinical discipline. • Minimum 10 years of experience in pharmaceutical or biotech R&D. • Demonstrated experience applying imaging in interventional clinical trials. • Prove

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