Vice President, Head of Clinical Operations

About this role

Your work will change lives. Including your own.

The Impact You’ll Make

At Recursion, we are decoding biology to radically improve lives. As Vice President, Head of Clinical Operations, you will own clinical operations strategy and execution across Recursion’s development portfolio from study planning through study closeout, data delivery, inspection readiness, and registrational support.

This is a portfolio-wide leadership role for an experienced clinical operations leader who can build scalable operating models, lead high-performing teams, manage global trials, and ensure operational excellence across early and late-stage clinical programs. You will also help define what modern clinical operations look like in an AI-native TechBio company: data-driven, quality-focused, patient-centered, technology-enabled, and built to move with urgency because patients are waiting.

In this role, you will:

• Lead clinical operations strategy and execution across Recursion’s full clinical portfolio, from IND/CTA planning and first-in-human studies through proof-of-concept, pivotal trials, study closeout, and submission support

• Own end-to-end operational delivery, including study planning, feasibility, country and site strategy, start-up, enrollment, monitoring, vendor oversight, budget management, database lock readiness, and closeout

• Build, scale, and mentor a high-performing Clinical Operations organization, including clinical project management, clinical trial management, outsourcing/vendor oversight, and portfolio operations capabilities

• Establish portfolio-level governance, operating rhythms, KPIs, dashboards, risk management, resource planning, and escalation pathways to support timely, high-quality trial execution

• Lead CRO and vendor strategy relationships, including outsourcing model, selection, contracting partnership, performance management, issue escalation, budget forecasting, and accountability for delivery

• Ensure inspection-ready execution across all studies through strong GCP compliance, SOP adherence, TMF oversight, risk-based quality management, audit readiness, CAPA management, and proactive issue resolution

The Team You’ll Join

You will join Recursion’s Clinical Development organization, reporting to our Chief Medical Officer. The Clinical Development team is an empowered, execution-minded group responsible for translating Recursion’s innovative science into medicines for patients.

You will work closely with leaders across Development, Regulatory, Development Sciences, Clinical Operations, Data Science, Biology, Chemistry, Portfolio Strategy, Communications, Legal/Compliance, and future commercialization functions. Together, you will help ensure Recursion’s clinical programs are informed by robust evidence, external medical insight, patient need, and the full potential of the RecursionOS.

The Experience You’ll Need

• Bachelor’s degree in a scientific, healthcare, or related field required; advanced degree preferred

• 15+ years of biotech or pharmaceutical clinical operations experience, including significant leadership experience overseeing multiple clinical programs and global clinical trials

• Proven track record leading clinical operations from early development through pivotal studies, registration-enabling trials, study closeout, and submission support

• Deep experience with clinical trial planning and execution, including feasibility, start-up, enrollment, monitoring, vendor/CRO oversight, budget management, risk management, database lock, and closeout

• Strong working knowledge of FDA, EMA, MHRA, ICH/GCP, global clinical trial regulations, quality systems, inspection readiness, and risk-based quality management

• Experience building and leading teams, including leaders of clinical operations, clinical project managers, clinical trial managers, consultants, CRO partners, and functional vendors

• Strong executive presence with the ability to communicate clearly, influence senior stakeholders, resolve complex operational issues, and drive decisions in a fast-moving environment

• Experience in oncology, rare disease, and/or specialty clinical development preferred; experience with clinical trial technologies, CTMS/eTMF/EDC/IRT/eCOA, operational dashboards, automation, or AI-enabled workflows is a plus

Working Location & Compensation:

This is a fully remote opportunity with occasional travel requirements. Travel may be necessary from time to time to support collaboration, team events, customer meetings, or other business needs.

At Recursion, we believe that every employee should be compensated fairly. Based on the skills, experience, and qualifications needed for this role, the estimated annual base salary range is:

• New York City, Boston, & San Francisco Bay Area(s): $333,000–$400,510

• Salt Lake City & all other U.S. locations: $303,600–$364,100

In addition to base salary, this role is eligible for an annual bonus, equity compensation, and a comprehensive benefits package.

#LI-DB1

#LI-REMOTE The Values We Hope You Share:

• We act boldly with integrity. We are unconstrained in our thinking, take calculated risks, and push boundaries, but never at the expense of ethics, science, or trust.

• We care deeply and engage directly. Caring means holding a deep sense of responsibility and respect - showing up, speaking honestly, and taking action.

• We learn actively and adapt rapidly. Progress comes from doing. We experiment, test, and refine, embracing iteration over perfection.

• We move with urgency because patients are waiting. Speed isn’t about rushing but about moving the needle every day.

• We take ownership and accountability. Through ownership and accountability, we enable trust and autonomy—leaders take accountability for decisive action, and teams own outcomes together.

• We are One Recursion. True cross-functional collaboration is about trust, clarity, humility, and impact. Through sharing, we can be greater than the sum of our ind

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