Vice President, Global Commercial Strategy Lead, Inflammation & Immunology + Rare Disease

About this role

Position Overview  The  Vice President, Global Commercial Strategy Lead for Inflammation & Immunology (I&I) and Rare Disease is responsible for driving long-range commercial strategy, portfolio management, and commercial success across both pipeline and inline brands. This role serves as the  single, authoritative commercial voice to R&D, Business Development, and US & International Commercial Regions , establishing clear commercial leadership to improve portfolio decision-making and trade-offs, ensure optimal launch and brand marketing strategies, and maximize global patient impact and enterprise value realization for our I&I and Rare Disease portfolio. 

Reporting to the Global Commercial Strategy Lead, this leader shapes decisions on I&I and Rare Disease portfolio prioritization, lifecycle value optimization, and global marketing strategy. The position partners closely with R&D, Medical Affairs, Global Access & Value, and Regional Commercial teams to deliver breakthrough therapies addressing autoimmune, inflammatory, and rare diseases.

Success in this role requires a senior commercial strategist who combines scientific depth with decisive enterprise leadership. This leader must confidently engage in complex scientific and clinical discussions, synthesize insights across R&D, Access, and Commercial teams, and convert them into clear portfolio priorities and differentiated global strategies. With full accountability for value creation, the role requires strong P&L acumen and the ability to make disciplined trade‑offs that optimize lifecycle value, launch success, and long‑term portfolio performance.

The I&I and Rare Disease portfolio represents significant strategic value to realizing Pfizer's vision to achieve leadership via breakthroughs in prioritized diseases and biological axes to generate highly differentiated, multi-indication mega-blockbusters. Today, the portfolio delivers more than $10B globally with 22 ongoing clinical studies underway to significantly expand our product portfolio over the next several years. Role Responsibilities  1. Long-Range Strategic Planning & Portfolio Management  • Develop and execute comprehensive long-range commercial and marketing strategies for I&I and Rare Disease portfolios, encompassing pipeline assets from early development to in-line assets through commercial maturity. • Serve as single, authoritative commercial voice to R&D, Commercial Regions, and Business Development strengthening commercial input from early development through launch via participation in I&I Strategy Governance Team to influence clinical development plans and investment decisions. • Lead development of business cases for new product launches and lifecycle management investments.

2. Launch Excellence & Commercialization Strategy  • Lead integrated global launch and marketing strategies coordinating cross-functional teams across R&D, Commercial Regions, Medical, Regulatory, Market Access, and Supply. • Drive new product and indication launch readiness planning including market development activities, brand positioning, competitive assessments, and HCP/patient unmet need analysis. • Own commercial asset lifecycle strategy for I&I and Rare Disease including implications of new indications and competitive dynamics   

3. Commercial Excellence & Brand Strategy  • Raise the bar on marketing impact, quality, and brand performance by establishing consistently higher, impact-driven standards for strategic outputs and creative excellence • Lead proactive market shaping in moments that matter, anticipating and addressing threats with pre-emptive strategies. • Steer Commercial prioritization of evidence generation strategies across lifecycle and Regions to enable sharper cross-functional decisions and portfolio value maximization.

4. Cross-Functional Leadership & Governance  • Provide global strategic direction for in-line assets while enabling regional adaptation and tactical alignment. • Own global brand strategy, launch plans, lifecycle management, and core content packages • Partner with Global Access & Value (GAV) teams to develop pricing, contracting, and market access strategies that maximize global value of our portfolio. 

5. Organizational Leadership & Talent Development  • Build and lead high-performing Global Commercial Strategy organization of 50+ highly engaged colleagues. • Embed culture of cross-functional collaboration ensuring coordinated internal and external stakeholder engagement. • Develop future commercial leaders with the capability to operate across full span of commercial development, launch, and in‑line commercialization.

Qualifications & Experience  Education   • Bachelor's degree in Life Sciences, Business, Marketing, or related field required • MBA or other advanced degree (PhD, MD, PharmD) strongly preferred

Professional Experience   • Minimum 15+ years  of successful, progressive marketing, commercial, and/or development experience in pharmaceutical or biotechnology industry • Minimum 8-10 years  in commercial leadership roles including Global/US/International marketing, commercial development/strategy • Experience in both pipeline (pre-launch) and inline (post-launch) brand management  spanning early development through commercialization

Therapeutic Area & Functional Expertise   • Brand management experience  developing product strategies, positioning programs, and go-to-market plans  • Product launch experience  including global launch planning and execution  • Portfolio management and strategic planning  expertise across multiple therapeutic areas and development stages  • Demonstrated ability to influence complex development decisions and engage deeply in scientific dialogue.

Leadership & Organizational Capabilities   • Second-line leadership experience  with accountability for developing and managing senior leaders  • Demonstrated ability to lead cross-functional teams and influencing without direct authority  while managing complex stakeho

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