Staff Scientist - Neurosurgery

About this role

Location SAINT LOUIS, MO 63110

 Scheduled Hours 40

Position Summary The Staff Scientist will provide advanced technical support for translational immunology and neuro-oncology research focused on T-cell trafficking, tumor immunology, and CAR-T cell therapy for brain tumors. The researcher will perform and optimize complex laboratory procedures including tissue and blood processing, multiparameter flow cytometry, immunofluorescence and immunohistochemical staining, cell culture, CAR-T cell functional assays, cytokine analyses, molecular biology techniques, and animal tumor studies.

The individual will be responsible for data collection, quality control, laboratory recordkeeping, and analysis of experimental results.

Job Description

Primary Duties & Responsibilities:

• Following instructions and discussions with the principal investigator, design research protocols, including developing procedures for the collection, verification and management of data. • Process brain tumor and peripheral blood specimens. • Perform flow cytometry, T-cell phenotyping, and functional immune assays. • Conduct immunofluorescence, immunohistochemistry, and image analysis. • Generate and evaluate CAR-T cells using in vitro cytotoxicity assays. • Perform cytokine profiling, ELISA-based assays, and molecular biology workflows. • Support murine brain tumor studies, including treatment administration and tissue collection. • Maintain experimental datasets, perform basic statistical analyses, and ensure rigorous documentation and quality control. • Document research topics and prepare and submit papers based on research work to publications and committees for publication or presentation to peers.

Working Conditions:

• Works in a laboratory environment with potential exposure to biological and chemical hazards. • Must be physically able to wear protective equipment and to provide standard care to research animals.

The above statements are intended to describe the general nature and level of work performed by people assigned to this classification. They are not intended to be construed as an exhaustive list of all job duties performed by the personnel so classified. Management reserves the right to revise or amend duties at any time.

Required Qualifications

Education: Master’s degree or combination of education and/or experience may substitute for minimum education. Certifications /Professional Licenses : No specific certification/professional license is required for this position.

Work Experience: Laboratory Operations (3 Years) Skills: Not Applicable Driver's License: A driver's license is not required for this position.

More About This Job WashU seeks highly motivated individuals who are able to perform duties in a manner consistent with our core mission and guiding principles.

Preferred Qualifications

Education: Ph.D. - Doctor of Philosophy Certifications /Professional Licenses : No additional certification/professional licenses unless stated elsewhere in the job posting. Work Experience: No additional work experience unless stated elsewhere in the job posting.

Skills: Analytical Problem Solving, Communication, Computer Literacy, Data Analysis, Data Interpretations

Grade R10

Salary Range $48,000.00 - $86,900.00 / Annually

The salary range reflects base salaries paid for positions in a given job grade across the University. Individual rates within the range will be determined by factors including one's qualifications and performance, equity with others in the department, market rates for positions within the same grade and department budget.

Questions For frequently asked questions about the application process, please refer to our External Applicant FAQ .

Accommodation If you are unable to use our online application system and would like an accommodation, please email   CandidateQuestions@wustl.edu   or call the dedicated accommodation inquiry number at 314-935-1149 and leave a voicemail with the nature of your request.

All qualified individuals must be able to perform the essential functions of the position satisfactorily and, if requested, reasonable accommodations will be made to enable employees with disabilities to perform the essential functions of their job, absent undue hardship.

Pre-Employment Screening All external candidates receiving an offer for employment will be required to submit to pre-employment screening for this position. The screenings will include criminal background check and, as applicable for the position, other background checks, drug screen, an employment and education or licensure/certification verification, physical examination, certain vaccinations and/or governmental registry checks. All offers are contingent upon successful completion of required screening.

Benefits Statement Personal • Up to 22 days of vacation, 10 recognized holidays, and sick time.

• Competitive health insurance packages with priority appointments and lower copays/coinsurance.

• Take advantage of our free Metro transit U-Pass for eligible employees.

• WashU provides eligible employees with a defined contribution (403(b)) Retirement Savings Plan, which combines employee contributions and university contributions starting at 7%.

Wellness • Wellness challenges, annual health screenings, mental health resources, mindfulness programs and courses, employee assistance program (EAP), financial resources, access to dietitians, and more!

Family • We offer 4 weeks of caregiver leave to bond with your new child. Family care resources are also available for your continued childcare needs. Need adult care? We’ve got you covered.

• WashU covers the cost of tuition for you and your family, including dependent undergraduate-level college tuition up to 100% at WashU and 40% elsewhere after seven years with us.

For policies, detailed benefits, and eligibility, please visit: https://hr.wustl.edu/benefits/

EEO Statement Washington University in St. Louis is committed to the principles and pract

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