Sr. Technical Program Manager, Infrastructure Engineering

About this role

The Role: Moderna is seeking a Senior Technical Program Manager (TPM) to drive project and program management of infrastructure (cloud and on-prem) rationalization and AI-readiness initiatives at Moderna globally. We’re looking for someone with a high level of integrity and personal accountability, strong interpersonal skills, and infrastructure technology domain expertise.  

Here’s What You’ll Do • Program Management – take a structured, data-driven, and risk-based approach to program scoping, execution, and reporting 

• Kick off and successfully manage multiple, simultaneous, complex, high visibility workstreams with full ownership, effective collaboration, and good process 

• Build processes, templates, and structure, or leverage existing ones as appropriate 

• Manage vendors, schedule, scope, and cost 

• Measure program success (or lack thereof) and risks using data and facts 

• Provide balanced risk remediation strategies and recommendations and drive risk mitigation 

• Develop and maintain close stakeholder relationships and build influence to drive the appropriate outcomes across Moderna 

• Provide clear, accurate, consistent, and timely communications 

• Advance good infrastructure and security practices and culture 

• Partner Collaboration work with Cloud Engineering, Systems Engineering, and AI Engineering, as well as Network Engineering, Identity and Access Management, Builder Tools & Platforms, IT, Cybersecurity, software engineering, and business stakeholders to manage and drive improvement projects in a structured and predictable manner 

• Manage multiple initiatives: 

• Cloud modernization  

• Rationalize infrastructure platforms, tooling, and service models that underpin AI workloads.  

• Identify and eliminate redundant, unsupported, or non‑scalable infrastructure patterns that impede AI adoption. 

• Enable standardized, secure, and supportable “AI‑ready” infrastructure foundations that accelerate time‑to‑value while managing cost and risk. 

• Ensure infrastructure rationalization aligns with AI governance, data protection, and compliance requirements. 

• Define and track KPIs related to platform consolidation, cost optimization, risk reduction, and AI enablement readiness. 

• Lead and drive infrastructure service management improvements and process optimization initiatives, including infrastructure patch and vulnerability management. 

• Actively contribute to creating a more inclusive culture and environment at Moderna; endorse, create, and maintain antiracist policies and processes

Here’s What You’ll Need (Minimum Qualifications) • 8+ years of program management experience, preferably in infrastructure engineering 

• Demonstrated technical depth, problem-solving capabilities, and stakeholder and vendor management skills 

• Technical background in infrastructure engineering, with a strong understanding of ITSM 

• Experience in running programs within a cross-functional, global team of mixed engineering, architecture, and operations. 

• Ability to successfully scope and drive complex and multi-workstream programs in a structured, risk-considerate, data-driven fashion 

• Strong listener with the ability to deeply understand, ask the right questions, and proactively pursue constructive feedback 

• Proven ability to operate in highly matrixed environments and influence without direct authority. 

Here’s What You’ll Bring to the Table (Preferred Qualifications) • Strong understanding of cloud platforms (AWS, Azure) 

• Familiarity with infrastructure concepts: compute, storage, networking, containers, Kubernetes 

• Working knowledge of AI/ML infrastructure needs (GPUs, distributed training, data pipelines, MLOps) 

• Influential, inclusive, and trusted partner compassionate to the needs and situations of all your stakeholders 

• Deep familiarity with ITSM frameworks (e.g., ITIL) 

• Experience driving structured, process-driven infrastructure transformation initiatives. 

• Knowledge of security and compliance standards relevant to infrastructure operations. 

• Embrace a culture of continuous service improvement and service excellence 

• A desire to make an impact as part of a high-growth, transformational company 

• Experience with GxP environments and regulatory requirements

Pay & Benefits At Moderna, we believe that when you feel your best, you can do your best work. That’s why our benefits and well-being resources are designed to support you—at work, at home, and everywhere in between. • Competitive healthcare, plus voluntary benefit programs to support your unique needs • A holistic approach to well-being, with access to fitness, mindfulness, and mental health support • Family planning benefits, including fertility, adoption, and surrogacy support • Generous paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown • Savings and investments to help you plan for the future • Location-specific perks and extras

The salary range for this role is $145,900.00 - $234,200.00. This is the lowest to highest salary we in good faith believe we would pay for this role at the time of this posting. An individual’s position within the salary range will be based on several factors including, but not limited to, specific competencies, relevant education, qualifications, certifications, experience, skills, performance, and business or organizational needs.

The successful candidate may be eligible for an annual discretionary bonus, other incentive compensation, or equity award, subject to company plan eligibility criteria and individual performance. About Moderna Since our founding in 2010, we have aspired to build the leading mRNA technology platform, the infrastructure to reimagine how medicines are created and delivered, and a world-class team. We believe in giving our people a platform to change medicine and an opportunity to change the world.  

By living our mission, values, and

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