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Sr Systems Administrator

Natera

Boulder, CO, USonsite

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About this role

Position Summary

Natera is looking for a Sr Systems Administrator to be the on-site go-to person for IT Infrastructure and Employee Care at our Boulder office. You'll be the person who keeps day-to-day operations running smoothly while serving as a local extension of our centralized IT Employee Care and Infrastructure team. This is a hands-on role that will own end-user support, site infrastructure, networking, and equipment connectivity for a site with roughly 25–75 people. You'll partner closely with our central IT group on configurations, standards, security, and larger projects. As the senior on-site IT resource, you'll operate a level above the day-to-day ticket queue — owning Level 2–3 escalations and acting as the local point of engagement and operational support for business and lab operations.

PRIMARY RESPONSIBILITIES:

Escalation & Employee Care

• Own Level 2–3 escalations for the site, serving as the senior technical resource for complex issues beyond the L1 ticket queue.

• Provision, image, deploy, and maintain laptops, desktops, and workstations.

• Support and troubleshoot printers, peripherals, conference room / AV systems, and other office hardware.

• Onboard and offboard local employees, including account, device, and access setup in coordination with central IT.

• Engage off-hours support for site-critical issues and provide an on-site escalation backstop.

Infrastructure, networking & connectivity

• Help support site networking alongside the Network Operations Team.

• Act as remote hands to help troubleshoot switches, firewalls, Wi-Fi, and internet connections.

• Manage connectivity for lab and specialized equipment, ensuring instruments and workstations stay reliably connected to the network.

• Monitor site infrastructure and proactively address issues before they impact the team.

Site operations & leadership

• Act as the on-site resource for infrastructure and employee care operations.

• Partner with the centralized IT team to roll out standards, tools, security practices, and projects locally.

• Manage local hardware inventory, procurement requests, and vendor relationships, including outsourced services

• Manage building access, utilities, environmental safety, and local regulatory compliance.

• Document local systems, processes, and runbooks.

QUALIFICATIONS:

• 7+ years in IT support / operations, with demonstrated growth from service desk to infrastructure and systems work.

• Strong end-user support skills paired with solid infrastructure fundamentals.

• Working knowledge of networking fundamentals: switches, firewalls, Wi-Fi, DNS/DHCP, VPNs, and ISP coordination.

• Experience deploying and managing endpoints (laptops, desktops, workstations) and associated tooling (MDM/imaging).

• Hands-on experience supporting enterprise systems such as Google Workspace, Zoom, and Atlassian. Familiarity with other enterprise business SaaS applications a plus

• Experience owning Level 2–3 escalations and acting as a senior point of resolution above a first-line support queue.

• Experience coordinating with offshore, managed, or outsourced support teams across time zones.

• Self-directed and dependable — able to run a site independently while staying aligned with a central team.

• Clear communicator who can support both technical and non-technical colleagues.

• Experience in healthcare, life sciences, or other regulated industries preferred

• Strategic and execution-oriented; able to think globally while acting locally.

• Comfortable in both leadership and hands-on operational roles.

• Excellent interpersonal skills for engaging internal stakeholders, external vendors, and customers.

• Pragmatic, resourceful, and able to thrive in an entrepreneurial environment.

NICE TO HAVE:

• Experience supporting lab, scientific, or specialized equipment connectivity.

• Server, storage, or virtualization administration experience.

• Exposure to security/compliance practices (endpoint security, access management).

• Prior experience as a site lead.

• Relevant certifications (e.g., Google Workspace Admin, CompTIA Network+/Security+, networking vendor certs).

OUR OPPORTUNITY

Natera™ is a global leader in cell-free DNA (cfDNA) testing, dedicated to oncology, women’s health, and organ health. Our aim is to make personalized genetic testing and diagnostics part of the standard of care to protect health and enable earlier and more targeted interventions that lead to longer, healthier lives.

The Natera team consists of highly dedicated statisticians, geneticists, doctors, laboratory scientists, business professionals, software engineers and many other professionals from world-class institutions, who care deeply for our work and each other. When you join Natera, you’ll work hard and grow quickly. Working alongside the elite of the industry, you’ll be stretched and challenged, and take pride in being part of a company that is changing the landscape of genetic disease management.

WHAT WE OFFER

Competitive Benefits - Employee benefits include comprehensive medical, dental, vision, life and disability plans for eligible employees and their dependents. Additionally, Natera employees and their immediate families receive free testing in addition to fertility care benefits. Other benefits include pregnancy and baby bonding leave, 401k benefits, commuter benefits and much more. We also offer a generous employee referral program!

For more information, visit www.natera.com .

Natera is proud to be an Equal Opportunity Employer. We are committed to ensuring a diverse and inclusive workplace environment, and welcome people of different backgrounds, experiences, abilities and perspectives. Inclusive collaboration benefits our employees, our community and our patients, and is critical to our mission of changing the management of disease worldwide.

All qualified applicants are encouraged to apply, and will be considered without regard to race, color, religion, gender, gender

Salary insight

This posting doesn't disclose pay. Across 354 Denver jobs with disclosed salaries on ForgeApply, the median is $140k.

Based on live postings with disclosed pay on ForgeApply; refreshed daily. Not an estimate of this employer's offer.

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