Sr. Supply Chain Optimization Manager

About this role

McKesson is an impact-driven, Fortune 10 company that touches virtually every aspect of healthcare. We are known for delivering insights, products, and services that make quality care more accessible and affordable. Here, we focus on the health, happiness, and well-being of you and those we serve – we care.

What you do at McKesson matters. We foster a culture where you can grow, make an impact, and are empowered to bring new ideas. Together, we thrive as we shape the future of health for patients, our communities, and our people. If you want to be part of tomorrow’s health today, we want to hear from you.

About the Role McKesson is seeking a strategic and results-driven Senior Supply Chain Optimization Manager to lead enterprise-scale initiatives that improve supply chain performance, enhance customer experience, and drive measurable business outcomes. This role serves as a trusted advisor to senior leaders, identifying opportunities to optimize inventory, logistics, sourcing, fulfillment, and operational processes across the supply chain. As a senior individual contributor, you will lead complex cross-functional projects from strategy development through implementation and value realization. The ideal candidate brings deep supply chain expertise, strong analytical problem-solving capabilities, and the ability to influence stakeholders across multiple functions in a fast-paced environment.

What You'll Do • Lead strategic supply chain transformation and optimization initiatives across inventory management, logistics, sourcing, distribution, and operations. • Identify, evaluate, and prioritize opportunities to improve service levels, operational efficiency, cost performance, and customer experience. • Develop business cases, project plans, executive presentations, roadmaps, risk assessments, and implementation strategies. • Lead complex cross-functional projects from concept through execution and benefit realization. • Partner with business leaders and stakeholders to define requirements, align priorities, and drive successful outcomes. • Analyze operational data, performance metrics, and market trends to identify improvement opportunities and recommend solutions. • Apply continuous improvement methodologies to optimize processes and enhance supply chain capabilities. • Drive organizational alignment, stakeholder engagement, and change management activities. • Present recommendations, project status, risks, and business impact to senior leadership. • Serve as a subject matter expert on supply chain optimization, process improvement, and operational excellence.

Basic Requirements • Bachelor's degree in Supply Chain Management, Operations, Business Administration, Industrial Engineering, Logistics, or a related field, or equivalent experience. • Typically requires 7+ years of relevant professional experience in supply chain, logistics, operations, procurement, inventory management, demand planning, transportation, or business process improvement. • Experience leading complex cross-functional projects and enterprise initiatives. • Demonstrated experience using data and analytics to drive operational improvements and business decisions. • Experience developing business cases, executive presentations, project plans, and implementation roadmaps. • Strong knowledge of supply chain operations, including at least one of the following: inventory management, logistics, transportation, sourcing, procurement, demand planning, distribution, or fulfillment. • Proven ability to influence stakeholders and drive results without direct authority.

Preferred Skills/Experience • Lean, Lean Six Sigma, Continuous Improvement, or Operational Excellence certification. • Experience leading supply chain transformation initiatives. • Advanced analytical skills using Excel, Power BI, Tableau, SQL, or similar tools. • Experience supporting large-scale organizational change and process reengineering efforts. • Healthcare, pharmaceutical, medical-surgical, distribution, manufacturing, or logistics industry experience. • Knowledge of supply chain systems such as SAP, Oracle, Blue Yonder, Manhattan, Kinaxis, or related platforms. • Project Management Professional (PMP) certification or comparable project management experience. • Strong executive presentation and stakeholder management skills.

Travel / Work Arrangement / Physical Requirements • Position may require occasional travel (up to 15%) to support business initiatives, stakeholder meetings, or operational site visits. • Hybrid work arrangement, if applicable, based on business and location requirements. • Ability to remain stationary for extended periods while working at a computer and participating in meetings.

McKesson complies with all applicable U.S. immigration laws and regulations. The Company does not provide employer support or sponsorship for any immigration related employment benefit for this role. Applicants must be currently authorized to work in the United States on a fulltime basis without the need for employer support or sponsorship now or in the future. This includes having the legal right to work in the United States without the need for McKesson support or sponsorship for any immigration related employment authorization (e.g., H1B, O1, E3, H1B1, TN, F1 OPT, F1 STEM OPT, F1 CPT, etc.) now or in the future. If you will require McKesson to provide immigration support or sponsorship now or in the future, you should not apply for this position.

We are proud to offer a competitive compensation package at McKesson as part of our Total Rewards. This is determined by several factors, including performance, experience and skills, equity, regular job market evaluations, and geographical markets. The pay range shown below is aligned with McKesson's pay philosophy, and pay will always be compliant with any applicable regulations. In addition to base pay, other compensation, such as an annual bonus or long-term incentive opportunities may be offered. For

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