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Sr Software Engineer

Illumina

San Diego, CA, US$129k – $194konsite

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About this role

What if the work you did every day could impact the lives of people you know? Or all of humanity?

At Illumina, we are expanding access to genomic technology to realize health equity for billions of people around the world. Our efforts enable life-changing discoveries that are transforming human health through the early detection and diagnosis of diseases and new treatment options for patients.

Working at Illumina means being part of something bigger than yourself. Every person, in every role, has the opportunity to make a difference. Surrounded by extraordinary people, inspiring leaders, and world changing projects, you will do more and become more than you ever thought possible.

We are looking for an experienced software engineer to join our Instrument Software team. This team develops software that is an integral part of Illumina’s growing fleet of Next Generation Sequencing (NGS) and related products . This role requires a professional with experience developing and delivering complex software projects. This crucial role focuses on developing mission-critical platform services responsible for the reliable movement, storage, and management of sequencing data generated by Illumina instruments. These services must operate reliably in the presence of network interruptions, system restarts, power loss events, and other real-world failures while ensuring data integrity and recoverability.  

Key Responsibilities:  

• Development : Develop, integrate, and debug platform software components responsible for the secure and reliable transfer, storage, and management of sequencing data, ensuring correctness and recoverability under real-world failure conditions.  

• Testing: C ontribut e to our exist ing CI/CD build pipelines, test environments, and automation infrastructure.  

• Component Design: Evaluate the detailed design of components , identify risks and improvement opportunities, and collaborate with technical leaders to drive continuous improvement .  

• Stakeholder Collaboration: Collaborate with multiple software teams to understand development needs, identify and address gaps in the platform , and drive change within areas of expertise.  

• Innova tion: Drive innovation at a software component and sub-system level and contribute ideas to software road mapping. Maintain awareness of industry trends and contribute to the evaluat ion of new software technologies.  

• Problem Solving: Leverage expertise in investigation and resolution of technical problems within the department . Assist in t roubleshoot ing complex customer issues potentially involving multiple components of the software system.  

Qualifications:  

• Education: Bachelor's degree in a relevant engineering field (e.g., Computer Science, Biomedical Engineering, Software Engineering).  

• Experience: Minimum of 5 years of experience in software development . Experience within the Medical or Life Sciences industry is a plus.  

• Collaboration : Excellent communication and interpersonal skills. Demonstrated success in collaborating in a fast-paced team environment and delivering high-quality software products using established agile development methodologies (such as Scrum, Kanban, etc.) against formal schedules.  

• Troubleshooting and Problem Solving : Demonstrated experience designing and implementing fault-tolerant distributed or multi-process systems. Experience with retry strategies, durable state management, idempotent operations, concurrency, asynchronous processing, and system recovery techniques is highly desirable.  

• Communication: Exceptional communication and interpersonal skills. Ability to adapt to a diverse environment and work effectively in a global team.  

• Technical Skills: Strong professional experience developing software in C# and .NET/.NET Core is required . Understanding of object-oriented analysis and design. Experience with testing frameworks like MSTest , xUnit , NUnit , or similar . Experience with Go ( golang ) and developing software for complex hardware systems are both a plus.  

• Domain Knowledge: Proven ability to analyze and contribute to software component design. Knowledge of hardware development, medical software, healthcare regulations, cybersecurity best practices , network protocols, or file transfer protocols are all highly desirable. Experience with NGS and Bioinformatics is a plus.  

Additional Skills :  

• Proven track record of designing and implementing robust software solutions that meet demanding resiliency, availability, and performance objectives .  

• Required experience with tools such as J ira , Confluence, GitHub , GitHub Actions, TeamCity , Jenkins or their equivalents .  

• Required experience designing and implementing software quality patterns and practices (continuous integration, static analysis, unit testing, integration testing ) and developing software on Linux .  

• Required understanding of Service Oriented Architectures (e.g., microservices) , REST APIs, and other architectural patterns.  

• Experience leveraging AI-assisted development tools (e.g., GitHub Copilot, Cursor, Claude) to improve software engineering productivity.  

• Optional development experience with containers and container platforms (e.g., Docker, Kubernetes) , and event-driven design .  

• Optional experience with web testing frameworks like Mocha, Jest, Sele n ium / WebDriverIO , or similar.  

Why Join Us:  

• Opportunity to work on innovative products that make a real difference in healthcare and research.  

• Collaborative and supportive work environment.  

• Competitive salary and benefits package.  

• Professional growth and development opportunities .  

The estimated base salary range for the Sr Software Engineer role based in the United States of America is: $129,400 - $194,000. Should the level or location of the role change during the hiring process, the applicable base pay range may be updated accordingly. The range reflects long‑term growth in the r

Salary insight

The midpoint of this range ($162k) is about 9% above the median disclosed salary for San Diego roles listed on ForgeApply ($148k across 768 jobs).

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Based on live postings with disclosed pay on ForgeApply; refreshed daily. Not an estimate of this employer's offer.

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