Sr. Director, Epidemiology & RWE Analytics

About this role

Who We Are: Neurocrine Biosciences is a leading biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering, developing and commercializing life-changing treatments for patients with under-addressed neurological, psychiatric, endocrine and immunological disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, hyperphagia in Prader-Willi syndrome, endometriosis* and uterine fibroids*, as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For more than three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science. For more information, visit  neurocrine.com , and follow the company on  LinkedIn ,  X , Facebook and YouTube . ( *in collaboration with AbbVie )

At Neurocrine, strong leadership drives both business results and team success. We look for leaders who think strategically, anticipate what’s ahead and set clear direction, while building and empowering high-performing teams. Successful leaders foster an environment where people are motivated to do their best work and deliver meaningful, measurable impact through sound decision-making and accountability.

 About the Role: Provides senior leadership for enterprise-wide epidemiology and real-world evidence (RWE) strategy, governance, and execution across therapeutic areas and portfolios. Accountable for defining and delivering fit-for-purpose, consistent evidence strategies that support clinical development, regulatory submissions, medical affairs, and market access. Serves as a senior thought partner to R&D, Medical, Market Access, and Analytics leadership and leads teams responsible for high impact, externally facing epidemiologic and RWE programs. _ Your Contributions (include, but are not limited to): • Define and lead enterprise-wide epidemiology and RWE strategy, ensuring alignment with corporate objectives and cross-functional priorities across R&D, Medical, Market Access, and Analytics.

• Establish and oversee functional governance, including methodological standards, evidence quality expectations, prioritization frameworks, and ways of working across therapeutic areas.

• Translate enterprise RWE strategy into portfolio- and therapeutic-area-level evidence plans supporting development, launch, and lifecycle management.

• Serve as a senior advisor to executive and cross-functional leadership on population health, disease epidemiology, and real-world evidence.

• Drive evidence strategies that directly support regulatory submissions, HTAs, reimbursement decisions, and global value demonstration.

• Lead, coach, and develop Directors, Managers, and senior scientific staff; ensure effective talent development and succession planning.

• Oversee functional resourcing and budget management to ensure efficient, compliant, and high-quality execution.

• Partner closely with R&D leadership to integrate RWE into Phase 3 trial design and late-stage development, including external control arms, endpoint validation, and contextualization of clinical outcomes.

• Provide functional scientific accountability for epidemiology and RWE components of late-stage development programs.

• Ensure rigorous epidemiologic and observational methodologies are applied consistently across programs.

• Collaborate with Drug Safety and Pharmacovigilance (DSPV) on epidemiologic analyses supporting background rates, safety surveillance, post-marketing commitments, and risk assessment.

• Provide strategic oversight and input into clinical plans, publications, and integrated evidence strategies.

• Partner with HEOR and Market Access leadership to generate fit-for-purpose RWE demonstrating clinical value, effectiveness, cost-effectiveness, and budget impact.

• Ensure RWE outputs meet global payer, HTA, and regulatory evidentiary expectations, anticipating evolving requirements.

• Serve as a primary functional representative in scientific advice meetings and evidence discussions with regulatory agencies and HTA bodies.

• Engage and influence external stakeholders including regulators, academic experts, data partners, industry consortia, and advisory boards.

• Represent the Epidemiology & RWE function in governance forums, internal and external scientific engagements.

• Oversee and ensure consistency, scientific integrity, and quality of all epidemiology and observational research programs.

• Contribute to regulatory submission planning, including data strategies, integrated summaries, and evidence positioning.

• Develop and maintain functional processes, SOPs, and compliance frameworks to support scalable and high-quality evidence generation.

• Serve as the escalation point for complex scientific, regulatory, or payer-facing evidence issues.

• Perform other duties as assigned.

Requirements:

Typical Experience or Education: • Master's Degree AND 12+ years of relevant experience OR

• PhD, PharmD, or MD in Epidemiology, Public Health, or a related field AND 10+ years of pharmaceutical or biotech experience in epidemiology and/or real-world evidence. OR

• Previous management experience

Common Knowledge and Skills • Acts as a "trusted advisor" across the company and may be recognized as an external expert

• Provides strategy, vision and direction regarding issues that may have company-wide impact

• Requires in-depth knowledge of the functional area, business strategies, and the company’s goals

• Must be self-motivated and detail-oriented

• Ability to quickly learn and think independently

• Excellent leadership, coaching and employee development skills

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