Senior Director, Global Value & Access Strategy – Povetacicept Lead

About this role

Job Description Background and Job Description: Vertex Pharmaceuticals operates at the forefront of scientific innovation and has successfully developed and commercialized multiple breakthrough medicines for Cystic Fibrosis (CF), Casgevy, a gene therapy for sickle cell disease and beta-thalassemia and Journavx, a novel new treatment for moderate to severe acute pain. Vertex has more than a dozen ongoing research programs focused on the underlying mechanisms of other serious diseases including programs in kidney diseases, Type 1 diabetes, among others.

Povetacicept is a highly potent and effective dual antagonist of BAFF and APRIL pathways with potential best-in-class efficacy in patients with IgA nephropathy (IgAN).  IgAN is a serious, progressive, autoimmune disease of the kidney that can lead to end-stage-renal disease. IgAN is the most common cause of primary (idiopathic) glomerulonephritis worldwide.  Due to its mechanism of action as a dual BAFF/APRIL antagonist, povetacicept holds the potential to benefit patients for multiple additional serious diseases including other autoimmune kidney diseases and autoimmune cytopenias such as primary membranous nephropathy (pMN) and generalized myasthenia gravis (gMG).

Vertex is seeking a Senior Director of Global Value & Access Strategy (GVAS) for povetacicept, reporting to the ED Kidney Lead, to join our dynamic team in Boston, MA.  The Senior Director will be the Market Access Asset Lead for povetacicept in IgA nephropathy (IgAN) and future indications, including pMN and gMG.  In this capacity, the individual will be responsible for evolving the global price and access strategy (P&MA) for IgAN and driving development of the LCM/portfolio P&MA strategy, as well as leading the cross-functional, cross-regional Value & Access Strategy Working Team.  The successful candidate will serve as the voice of the payer internally to ensure that P&MA implications are considered in key program decisions. This role will also be accountable for leadership of cross-portfolio capability building and thought leadership projects that advance knowledge of and readiness for the rapidly evolving global payer environment.

The successful candidate will be strategic, demonstrate strong cross-functional leadership, thrive in complexity, and have a problem-solving mindset backed by strong analytical skills. The candidate must share our passion for science-based brands that can dramatically improve patients' lives.  As a senior member on the GVAS team, the successful candidate must be able to role model Vertex’s ethics & culture and be committed to developing the next generation of leaders.  They will also manage two direct reports.

Key Responsibilities:  • Responsible for evolving the overall development and communication of the Global pricing & market access strategy for povetacicept within cross functional, cross-regional commercialization processes. • Ensure global market access launch readiness for IgAN lead indication • Ensure delivery of differentiated branded, branded payer value communications and supportive training • Lead the evolution of the global price and market access strategy in IgAN • Partner cross-functionally and cross-regionally to ensure robust integrated evidence plans to support global market access and reimbursement at launch and over time

• Responsible for development of the P&MA strategies for future indications/portfolio • Partner within commercial to develop overall LCM strategy, including indication sequencing • Ensure P&MA strategies are supported by payer insights and robust global payer plans • Identify, prioritize and champion evidence required for access enabling trials and value optimization

• Provide leadership within the Global Commercial Model and shape commercial strategy; contribute directly to Commercialization Strategy Team and the Disease Strategy Team to ensure the payer position is consistently represented • Lead cross-portfolio capability building and thought leadership projects that advance knowledge of and readiness for the rapidly evolving Global payer environment • Effectively lead cross-functionally and cross-Regionally, particularly across Market Access teams, HEOR, Real World Evidence, Government Affairs and Public Policy and to ensure alignment around and delivery against access goals • Provide direct, “hands-on” development of strategic and tactical deliverables as required • Manage 2 direct reports

Experience & Qualifications:   • Bachelor’s degree required, ideally in life sciences, post graduate preferred • 12+ years of direct biotechnology / pharmaceutical industry experience; 5+ years of supervisory/management experience preferred • Deep working knowledge of both US and ex-US healthcare systems required; experience in a comparable global and/or specialty disease area role, especially involving product launches in highly competitive markets with potential for expansion into multiple indications, considered a plus • Demonstrated ability to think strategically and make sound pricing and market access recommendations • Strong practical, quantitative and analytical skills combined with a sound understanding of how to successfully apply pricing & reimbursement / HEOR principles to support Vertex • Exhibits outstanding written and oral communication skills, including the ability to effectively write and deliver presentations to professionals at all levels within Vertex • Demonstrated ability to manage initiatives that require cross-functional collaboration and relationships at all levels of the organization and across geographies • General experience in commercialization and drug development • Recognized as a team player with excellent interpersonal skills who is flexible and reliable • Displays sound ethics and a fit for Vertex’s core values and culture

Pay Range: $240,000 - $360,000 Disclosure Statement: The range provided is based on what we believe is a reasonable estimate for the base salary pay range for

Similar jobs

• Senior Director, US Market Access Strategy, Povetacicept (POVE) — Vertex · Boston, MA
• Director, Global Value & Access Strategy (Cell and Gene Therapy) — Vertex · Boston, MA
• Director, Market Access Strategy, Access Optimization Lead (Oncology) — GSK · Remote
• Senior Medical Director, Clinical Development- POVE — Vertex · Boston, MA
• Senior Director, PAVE Access Strategy & Marketing — Pfizer (Internaljobs) · New York City, New York, United States | Any Pfizer Site, United States
• Senior Director, PAVE Access Strategy & Marketing — Pfizer · New York City, New York, United States | Any Pfizer Site, United States
• Senior Director, Market Access Consulting — Precisionmedicinegroup · Remote
• Senior Director, Market Access Consulting — Precisionaq · New York, New York, United States