Senior Director / Director, Oncology Translational Medicine Project Manager

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Senior Director / Director, Oncology Translational Medicine Project Manager

The Oncology Translational Medicine (OTM) Planning & Execution team is a dedicated group of Scientific Operations, Project Management, and Alliance Management professionals that integrate, manage, and drive execution of OTM’s biomarker and diagnostic strategies across GSK’s global Oncology portfolio.

The Director, ADC Translational Medicine Project Manager, will partner closely with the ADC Translational Medicine Lead to translate their scientific strategy into robust, integrated project plans and drive flawless execution for the antibody–drug conjugate (ADC) portfolio.

This role is accountable for planning, execution, and stakeholder coordination across biomarkers, diagnostics, and clinical development; coordinating cross-functional teams (Biomarkers, Diagnostics, Clinical Pharmacology Modeling & Simulation, Clinical Development, Clinical Operations, Data Management, Statistics, Quality, Regulatory, Commercial, Finance) as well as external laboratories, collaborators, and diagnostic manufacturers. The Director will schedule and run ADC project meetings, maintain governance-ready dashboards and decision logs, oversee budgets, contracts, and resource needs, and ensure operational and inspection readiness for key translational and diagnostic milestones. By leveraging subject matter expertise in end-to-end biomarker-to-diagnostic strategic planning and execution, they will provide leadership and oversight to the translational medicine plan, ensure internal stakeholder alignment, manage risks and interdependencies, support regulatory submissions and compliance requirements, and deliver clear, insight-driven reporting to ADC core teams for R&D governance. Acting as a trusted project management advisor to the ADC TM Senior Matrix Leader, the Director will provide scenario-based analyses and drive continuous process improvements that enhance transparency, efficiency, and delivery across the ADC portfolio.

For candidates seeking to be located at our Stevenage site, this role will temporarily be based at Stevenage. However, the Company plans to relocate its offices to Cambridge, UK. The location of this role will therefore subsequently change to Cambridge, UK in accordance with timelines to be set by the Company. The relocation is currently proposed to take effect by early 2029.

Key Responsibilities • Translate the overarching ADC translational medicine strategy and vision into integrated, detailed project plans (scope, milestones, critical paths, dependencies, risks) across biomarkers, diagnostics, and clinical development • Monitor progress versus plan; proactively identify issues and interdependencies, escalate as needed, and coordinate cross-functional mitigation plans • Schedule, structure, and run ADC project team meetings (set agendas, pre-reads, minutes, action logs), track and drive closure of decisions and actions • Build and maintain governance-ready views (dashboards, status summaries, decision logs) to enable the ADC TM Lead to present and drive decisions at R&D governance, ADC MDTs, and external boards • Serve as the operational interface between internal teams and external partners (e.g., Joint Project Teams, diagnostic manufacturers), ensuring deliverables, timelines, and obligations are clearly understood and met • Support the ADC TM Lead and functional heads in forecasting and tracking TM resource needs (FTE, external partners) for the ADC portfolio; flag constraints and propose options • Coordinate diagnostic and biomarker-related budgets (as relevant): track spend vs. plan, support PO/invoice workflows, and reconcile against contracted scopes • Maintain oversight of relevant contracts and SOWs with external diagnostic partners to ensure alignment with TM plans and timelines • Establish and maintain a structured risk and issue management process for ADC TM activities (identification, impact assessment, mitigation/contingency, owners, timelines) • Ensure operational readiness for key TM and Dx milestones (e.g., data readouts, regulatory interactions, diagnostic readiness packages) and coordinate cross-functional readiness checks • Support compliance with regulatory and quality expectations by organizing documentation and tracking contributions to regulatory submissions and inspection-readiness activities related to biomarkers/Dx • Coordinate timelines and dependencies for generation of key translational data (biomarker, PK/PD, diagnostic) across studies, ensuring alignment with decision points and governance dates • Partner with scientific and data teams to build integrated status and insight reports that enable the ADC TM Lead to deliver succinct translational data narratives to ADC core teams and governance • Maintain shared repositories (SharePoint, dashboards, trackers) for TM plans, data summaries, and decision histories to improve transparency and continuity • Identify and implement operational improvements to increase TM team efficiency and focus on high-value scientific work • Provide high-quality project management support to the ADC TM Lead in their role as Senior Matrix Leader (e.g., preparing cross-indication overviews, aligning tumor indication leads on timelines and dependencies, consolidating risks) and act as a trusted PM advisor to the TM Lead, offering scenario analyses (timeline, cost, risk) to inform their strategic decisions on TM pl

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