Program Manager – Engineering Projects

About this role

Company Overview ImmunityBio, Inc. (NASDAQ: IBRX) is a commercial-stage biotechnology company developing cell and immunotherapy products that are designed to help strengthen each patient’s natural immune system, potentially enabling it to outsmart the disease and eliminate cancerous or infected cells. We envision a day when we no longer fear cancer, but can conquer it, thanks to the biological wonder that is the human immune system. Our scientists are working to develop novel therapies that harness that inherent power by amplifying both branches of the immune system, attacking cancerous or infected cells today while building immunological memory for tomorrow. The goal: to reprogram the patient’s immune system and treat the host rather than just the disease.

Why ImmunityBio? • ImmunityBio is developing cutting-edge technology with the goal to transform the lives of patients with cancer and develop next-generation therapies and vaccines that complement, harness and amplify the immune system to defeat cancers and infectious diseases. • Opportunity to join a publicly traded biopharmaceutical company with headquarters in Southern California. • Work with a collaborative team with the ability to work across different areas of the company. • Ability to join a growing company with professional development opportunities. Position Summary The Program Manager- Engineering Projects is responsible for the planning, execution, and delivery of facility and engineering projects that enable ImmunityBio’s clinical and commercial manufacturing operations, with a strong focus on facility buildouts, utilities, and equipment qualification and validation. This role leads cross-functional project teams through all phases of capital and infrastructure projects, from concept design and funding approval through construction, commissioning, qualification, and handover to operations. The Program Manager- Engineering Projects ensures programs are delivered safely, on schedule, within budget, and in compliance with cGMP, building codes, and internal quality standards.

Essential Functions • Owns end-to-end delivery of assigned facility, utility, and equipment projects from concept through turnover to Operations, acting as the primary point of contact for scope, schedule, budget, and quality. • Develops and maintains integrated program plans, including scope definition, milestones, resource plans, budgets, and risk registers for facility buildouts, renovations, and equipment installations. • Coordinates internal resources and external partners (contractors, vendors, commissioning and qualification providers) to execute the program scope in a highly regulated environment. • Leads regular project meetings, prepares status reports, and communicates progress, risks, and mitigation strategies to stakeholders and site leadership. • Identifies critical path activities, dependencies, and potential bottlenecks; develops and implements recovery plans as needed to maintain project commitments. • Plans, organizes, and directs a wide variety of capital projects including new construction, facility expansions, laboratory and cleanroom buildouts, and infrastructure upgrades. • Partners with Facilities, Manufacturing, Quality, EHS, and external design teams to ensure facility layouts and building systems (HVAC, utilities, process piping, electrical, controls) meet operational, regulatory, and safety requirements. • Partners with multiple project teams to ensure completion of all ongoing projects. • Ensures design and construction are aligned with cGMP requirements for biopharmaceutical operations, including controlled environments, material and personnel flows, and segregation strategies. • Monitors construction progress, reviews field changes, and assists in resolution of site issues; evaluates and recommends approval of change orders that impact scope, cost, or schedule. • Leads or coordinates commissioning and qualification activities for new and modified equipment, utilities, and systems in partnership with Engineering, Validation, and Quality. • Supports development and execution of CQV deliverables (URS, design reviews, FAT/SAT, IQ/OQ/PQ protocols, summary reports) to ensure equipment is fit for intended use and compliant with regulatory expectations. • Ensures program and project timelines account for CQV activities, documentation reviews, and regulatory/QA approvals required for GMP release. • Drives resolution of technical and validation issues during startup and qualification, coordinating cross-functional troubleshooting and escalation as needed. • Ensures projects are executed in compliance with applicable building and safety codes, environmental regulations, and company standards. • Partners with EHS to plan and monitor construction safety programs and ensure contractor compliance with site safety requirements. • Supports internal and external audits/inspections related to facilities, equipment, and validation, including preparation and presentation of project and CQV documentation. • Develops program and project budgets and cash flow forecasts; tracks and reports capital spend against approved funding. • Reviews and evaluates vendor and contractor proposals, scopes of work, and change orders; provides recommendations for selection and award. • Reviews invoices in line with completion milestones and contract terms. • Facilitates cross-functional communication and decision-making to ensure alignment between Engineering, Operations, Quality, Supply Chain, and other stakeholders. • Escalates key issues, risks, and decisions to leadership with clear options and recommendations. • Prepares and delivers project updates to executive and site leadership, including dashboards, presentations, and written reports.

Education & Experience • Bachelor’s degree in engineering, science or relevant field required. • 3+ years of engineering program/project management experience in biotechnology, pharmaceutical, or other regulated life scie

Similar jobs

• Senior Program Manager – Engineering Projects — ImmunityBio · Dunkirk NY
• Program Manager, Engineering-2 — Integer · Plymouth, MN
• Program Manager, Engineering-1 — Integer · Plymouth, MN
• Project Manager - Engineering — Catalent · Madison, WI
• Project Manager - Engineering — Oneok · Tulsa, OK
• Manager - Project Engineering — Sanimax · South St.Paul, Minnesota, United States
• Project Manager I - Engineering — Oneok · Medford, OK
• Project Manager I - Engineering — HNTB · Scott Depot, WV (Charleston)