Principal Systems Engineer

About this role

We anticipate the application window for this opening will close on - 12 Sep 2026   Careers that change lives start here. Medtronic is a global leader in healthcare technology with a Mission to alleviate pain, restore health, and extend life. Our 95,000 employees work across more than 150 countries to put patients first — developing innovative medical technologies that improve the lives of 72+ million patients each year. Your unique talents will help shape the future of healthcare while building a career grounded in purpose, growth, and impact.

A Day in the Life The Surgical Operating Unit develops products used across a broad range of surgical procedures, including wound management and hernia repair. This role supports a large, globally launched portfolio of sutures, needles, meshes, and related wound closure technologies with an emphasis on systems engineering excellence across the product lifecycle. The portfolio includes thousands of commercially available product configurations and requires close collaboration across Research and Development, Quality, Regulatory, Marketing, Manufacturing, and Released Product Engineering teams to ensure continued product performance, compliance, and business continuity. This position is based in North Haven, Connecticut and requires an onsite work arrangement. Limited travel may be required to support business needs, product evaluations, manufacturing activities, or cross-functional collaboration.                     As a Principal Systems Engineer, you will provide technical leadership for systems engineering activities supporting launched and incrementally developing wound management and hernia products. This role serves as a key systems engineering subject matter expert, driving requirements definition, risk management, design change assessments, technical investigations, and traceability activities across complex, high-volume product families. The position partners closely with cross-functional stakeholders to evaluate product impacts, enable informed technical decisions, and establish systems engineering best practices for the portfolio.

Primary Responsibilities • Lead systems engineering activities across wound management and hernia product families, including requirements management, risk management, verification and validation planning, and lifecycle support. • Establish and maintain intended use definitions, use cases, use conditions, stakeholder needs, design inputs, and end-to-end traceability across product and system requirements. • Assess the impact of design, process, material, manufacturing, and labeling changes on launched products and product families. • Drive technical investigations, root cause analyses, and cross-functional problem-solving activities to support product performance, quality, and regulatory compliance. • Evaluate system-level risks, tradeoffs, and design decisions to ensure alignment with customer needs, product requirements, manufacturing feasibility, and business objectives. • Apply systems engineering methodologies and best practices to improve consistency, efficiency, and technical rigor across the portfolio. • Partner with Research and Development, Quality, Regulatory Affairs, Manufacturing, Marketing, and Released Product Engineering teams throughout the product lifecycle. • Mentor and provide technical guidance to engineers and cross-functional team members on systems engineering processes, tools, and deliverables.

Required Qualifications • Bachelor's degree with 7+ years of relevant engineering experience, OR Master's degree with 5+ years of relevant engineering experience, OR PhD with 3+ years of relevant engineering experience. • Experience performing systems engineering activities within a regulated product development environment, including requirements management, risk management, verification, and validation. • Experience supporting design controls and product lifecycle activities for commercialized products. • Experience leading technical projects and influencing cross-functional stakeholders. • Ability to work onsite in North Haven, Connecticut.

Preferred Qualifications • Degree in Systems Engineering, Biomedical Engineering, Materials Science Engineering, Mechanical Engineering, or a related engineering discipline. • Experience within the medical device industry supporting wound management, sutures, needles, mesh, consumable products, or similar product portfolios. • Experience supporting high-volume product families with a large number of product configurations, stock keeping units (SKUs), or variants. • Experience with systems engineering tools and methodologies, including requirements traceability, risk analysis, and model-based systems engineering. • Experience supporting released products through design changes, product improvements, technical investigations, and manufacturing or quality-driven initiatives.

For Baccalaureate degrees earned outside of the United States, a degree that satisfies the requirements of 8 C.F.R. § 214.2(h)(4)(iii)(A) is required.

Physical Job Requirements

The above statements are intended to describe the general nature and level of work being performed by employees assigned to this position, but they are not an exhaustive list of all the required responsibilities and skills of this position. 

The physical demands described within the Responsibilities section of this job description are representative of those that must be met by an employee to successfully perform the essential functions of this job. Reasonable accommodations may be made to enable individuals with disabilities to perform the essential functions. For Office Roles: While performing the duties of this job, the employee is regularly required to be independently mobile. The employee is also required to interact with a computer, and communicate with peers and co-workers. Contact your manager or local HR to understand the Work Conditions and Physical requirements that may be specific to each role.

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