MariTide, OSA and PIE Program Execution Lead

About this role

Career Category Project Management Job Description

Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

MariTide, OSA and PIE Program Execution Lead

What you will do

Let’s do this. Let’s change the world. In this vital role under the direction of the Chronic Weight Management Global Indication Lead, this role responsible for shaping and driving enterprise integrated execution across MariTide lifecycle expansion initiatives, including Obstructive Sleep Apnea (OSA), Patient Impact Expansion (PIE), and future obesity franchise opportunities. The role serves as the integrator across obesity Obstructive Sleep Apnea (OSA) and Patient Impact Expansion (PIE), being accountable for enabling cross-functional decision-making, influencing portfolio prioritization, and driving successful delivery of key milestones that maximize patient and business impact.

Key Responsibilities: • Lead enterprise portfolio integration and strategic influence across the cross-functional execution of the OSA indication and PIE initiatives, ensuring alignment across development, medical, regulatory, commercial, and operations functions. 

• Shape and operationalize the integrated program plan and critical timelines, driving accountability, visibility, and delivery against key milestones.

• Drive execution excellence across Global Development, Medical, Commercial, Regulatory, Market Access, and Operations functions to ensure successful execution of interconnected portfolio initiatives, proactively identifying risks, dependencies, and trade-offs to enable timely, decision-ready outcomes.

• Translate strategy into actionable plans, ensuring clear linkage between global objectives and operational effectiveness to support launch readiness and lifecycle management.

• Lead cross-functional alignment and decision-making, serving as a central integrator to ensure clarity, speed, and coordinated execution and prioritization across stakeholders.

• Own integrated program processes, including development of recommendations, strategic options, and decision-enablement materials for senior leadership and governance forums, enabling efficient, data-driven decisions at key program milestones.

• Influence prioritization of activities and resources, aligning execution against highest-value opportunities and portfolio objectives.

• Embed continuous improvement and cross-program learning into execution to enhance team effectiveness, agility, and speed to patient.

• Partner with senior leadership to identify and mitigate enterprise risks, dependencies, and operational challenges impacting program delivery.

• Lead cross-functional planning processes and ensure linkage between global strategy, business priorities, and operational execution.

• Anticipate emerging portfolio risks, competitive developments, and strategic opportunities and provide recommendations to senior leadership regarding priorities and execution strategies.

• Drive collaboration across functions and geographies to support efficient execution and alignment with broader enterprise objectives.

What we expect of you

We are all different, yet we all use our unique contributions to serve patients. The professional we seek is a collaborative leader with these qualifications.

Basic Qualifications:

Doctorate degree and 5 years of biopharmaceutical commercialization, global strategy execution, or program management experience OR Master’s degree and 8 years of biopharmaceutical commercialization, global strategy execution, or program management experience OR Bachelor’s degree and 10 years of biopharmaceutical commercialization, global strategy execution, or program management experience

Preferred Qualifications:   • Consulting experience with a leading management consulting firm is highly preferred. 

• Demonstrated experience solving complex business problems in a consulting environment, including stakeholder management, data analysis, and strategic recommendations. 

• Strong analytical and problem-solving skills with experience managing multiple stakeholders and leading cross-functional initiatives. 

• Proven track record of leading complex, cross-functional programs through key development and commercialization milestones 

• Strong executive presence with experience supporting senior governance and decision-making forums 

• Demonstrated ability to influence without authority and drive alignment across diverse, global stakeholders 

Core Competencies:   • Strategic Execution, Operational Leadership and Commercialization  

• Cross-Functional Influence & Alignment 

• Program & Project Management Excellence 

• Executive Communication & Decision Enablement 

• Risk Management & Problem Solving 

• Agility and Continuous Improvement 

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefi

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