Infectious Disease In Vivo Cancer Vaccine Scientist

About this role

Job Description  

Here   at   AstraZeneca   you’ll   have the opportunity to make a difference in people’s lives every day. As one of the world’s premier biotechnology companies, our mission is centered on delivering life-changing products that advance world   health, and   help fight and cure disease. As a   Scientist   in the Virology and Vaccines Discovery group  in   the   early   Infectious Disease   therapeutic area   based   in   Gaithersburg, MD,   you’ll   play a pivotal role in channeling our scientific capabilities to make a positive impact on changing patients’ lives.   

The   Virology and Vaccines Discovery   group at   AstraZeneca   is   discover ing   and developing biologics and vaccines targeting key viral pathogens, including respiratory   and chronic   viruses.   We   are   cons istently   pushing the boundaries of science to deliver life-changing medicines to patients.   Our deep   expertise   in   vaccines and immunology   enable s our ability to advance   novel therapeutic approaches   and technologies   to prevent and treat infectious disease .   We   have   an   industry-leading   pipeline   and   offer a unique and strong collaborative network as part of the AstraZeneca family.  

Currently, we are   seeking   a highly motivated and broadly skilled bench scientist with   in vivo   technical   and immunolo g y   expertise   and   a track record   of scientific achievement to join the Virology and Vaccine Discovery group at AstraZeneca in Gaithersburg, MD. The   s cientist will be a key member of a team focused on developing next-generation   cancer   vaccines   through the drug discovery process. The position requires a strong interest in   vivarium and   laboratory bench work   to   driv e   projects forward.  

  AstraZeneca   has a dynamic environment that fosters collaboration and innovation. We attract top minds, and we nurture and build top talent.  

Major responsibilities :  

• Design, m anage ,   and conduct in vivo rodent studies to support the development of   cancer   vaccines targeting   host   tumor   antigens and   endogenous retroviruses  

• Perform   immunizations , tumor implantations,   and   necrops ies , collect and process tissues and blood products for downstream immunological assays  

• Conduct in vitro immunological assays to support the development of vaccines , including flow cytometry, ELISpot, and ELISA  

• Design, execute and interpret results from animal studies to characterize biologic therapies directed against   tumor antigens as   part of vaccine antigen discovery effort s  

• Work collaboratively with colleagues across the organization ( e.g.   protein engineering, bioinformatics, pathology, and translational medicine) to drive projects towards successful completion  

Requirements/ Qualifications :  

• B.S. in Virology, Molecular Biology, Microbiology, Immunology, Cell Biology, or related scientific discipline with   2 + years of experience   or    

• M.S. in Virology, Molecular Biology, Microbiology, Immunology, Cell Biology, or related scientific discipline  

Specific skills :  

Broad experience   desired   in   oncology,   immunolog y , and vaccinology  

• Advanced knowledge of   animal handling techniques, including intramuscular , intranasal, subcutaneous ,   and intravenous immunization s ,   and   euthanasia  

• Advanced knowledge of t umor   harvesting and   other tissue   processing,   i.e.   lymph nodes   and   spleen  

• Experience with mouse tumor model   development   is   strongly   desired  

• Knowledge   of flow cytometry   sample acquisition and data analysis   is   strongly   desired  

• Experience with automation is desired  

• Ability to multitask and prioritize   among   numerous   projects  

• Strong interpersonal and collaborative skills together with evidence of having used these to   support problem solving and delivery in a team-oriented, collaborative environment  

• Ability to work in a collaborative, fast-paced environment while planning and meeting timelines  

• Proven   track record   of success in your research and experience preparing written scientific   reports ( e.g.   manuscripts) and oral presentations ( e.g.   slides, posters)  

• Strong verbal and written communication skills  

Job complexity :   Must be able to understand,   conduct   and interpret results of technically challenging experiments with supervision.  

Supervision :   Ability to work independently as well as part of team is expected .  

To be considered for this exciting opportunity, please complete the full application on our website at your earliest convenience .  

AstraZeneca is an equal opportunity employer. AstraZeneca will consider all qualified applicants for employment without discrimination on grounds of disability, sex or sexual orientation, pregnancy or maternity leave status, race or national or ethnic origin, age, religion or belief, gender identity or re-assignment, marital or civil partnership status, protected veteran status (if applicable) or any other characteristic protected by law. AstraZeneca only employs individuals with the right to work in the country/ ies   where the role is advertised.  

The annual base pay (or hourly rate of compensation) for this position ranges from $92,252 to $130,378. Our positions offer eligibility for various incentives—an opportunity to receive short-term incentive bonuses, equity-based awards for salaried roles and commissions for sales roles. Benefits offered include qualified retirement programs, paid time off (i.e., vacation, holiday, and leaves), as well as health, dental, and vision coverage in accordance with the terms of the applicable plans.

Date Posted 07-ago-2026 Closing Date 13-ago-2026 Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified c

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