Head of Clinical Data Management

About this role

Who We Are: Neurocrine Biosciences is a leading biopharmaceutical company with a simple purpose: to relieve suffering for people with great needs. We are dedicated to discovering, developing and commercializing life-changing treatments for patients with under-addressed neurological, psychiatric, endocrine and immunological disorders. The company's diverse portfolio includes FDA-approved treatments for tardive dyskinesia, chorea associated with Huntington's disease, classic congenital adrenal hyperplasia, hyperphagia in Prader-Willi syndrome, endometriosis* and uterine fibroids*, as well as a robust pipeline including multiple compounds in mid- to late-phase clinical development across our core therapeutic areas. For more than three decades, we have applied our unique insight into neuroscience and the interconnections between brain and body systems to treat complex conditions. We relentlessly pursue medicines to ease the burden of debilitating diseases and disorders, because you deserve brave science. For more information, visit  neurocrine.com , and follow the company on  LinkedIn ,  X , Facebook and YouTube . ( *in collaboration with AbbVie )

At Neurocrine, strong leadership drives both business results and team success. We look for leaders who think strategically, anticipate what’s ahead and set clear direction, while building and empowering high-performing teams. Successful leaders foster an environment where people are motivated to do their best work and deliver meaningful, measurable impact through sound decision-making and accountability.

 About the Role: Provides enterprise-level leadership for the Clinical Data Management function and is accountable for the strategy, governance, operating model, and delivery of high-quality, inspection-ready clinical data across the clinical development portfolio. Ensures organizational capability, operational excellence, and scalable processes that support regulatory submissions, portfolio execution, and business objectives. _ Your Contributions (include, but are not limited to): • Lead the Clinical Data Management function and/or major CDM sub-functions across the clinical development portfolio to ensure accurate, complete, timely, high-quality, and inspection-ready clinical trial data deliverables

• Establish and evolve the CDM strategy, operating model, governance framework, resource planning approach, vendor ecosystem, and capability roadmap to support portfolio growth and business priorities

• Provide portfolio-level strategic and operational leadership across the clinical data lifecycle, including data collection strategy, EDC/database build strategy, external data integration, data review, reconciliation, database lock readiness, clinical data delivery, and vendor oversight

• Drive execution quality and predictability across the portfolio by establishing data quality plans, risk-based approaches, portfolio metrics, dashboards, governance mechanisms, and escalation pathways

• Ensure CDM provides early strategic input into protocol design, CRF design, data standards, endpoint implementation, data flow, and cross-study consistency to enable fit-for-purpose data collection and high-quality analysis-ready data

• Partner with senior leaders in Biostatistics and Statistical Programming to drive end-to-end traceability from protocol and CRF design through SDTM-ready and analysis-ready data, reducing downstream rework and improving analysis timelines

• Lead resolution of high-impact or cross-functional CDM issues, including data quality risks, database lock risks, external data reconciliation challenges, vendor performance concerns, submission-readiness issues, and process or operating model gaps

• Establish and oversee CRO, vendor, contractor, and external data provider governance models; ensure vendor strategy, performance, quality, timelines, issue resolution, and contractual deliverables support portfolio needs

• Represent CDM in senior cross-functional governance, portfolio, program, vendor, and operational forums; communicate risks, recommendations, decisions, tradeoffs, and progress to senior leadership

• Partner with Clinical Development, Clinical Operations, Biostatistics, Statistical Programming, Medical, Safety/PV, Regulatory, Quality, Clinical Systems/IT, and external partners to align CDM strategy with development priorities, regulatory expectations, program goals, and business needs

• Own development and continuous improvement of CDM processes, standards, templates, work practices, governance mechanisms, and quality frameworks to increase operational efficiency, inspection readiness, and consistency across the portfolio

• Lead CDM technology enablement and modernization strategy, including scalable EDC build approaches, standard libraries, reusable CRFs/edit checks, automation, AI-enabled data review workflows, data quality surveillance, and solutions supporting end-to-end biometrics standardization

• Ensure the CDM function operates in accordance with applicable regulations, Good Clinical Practice, ICH guidelines, Good Clinical Data Management Practices, SOPs, work instructions, data integrity expectations, and study-specific requirements

• Provide senior leadership for CDM-related inspections, audits, quality reviews, data integrity initiatives, submission-readiness activities, and corrective/preventive action plans

• Build, lead, and develop a high-performing CDM organization; manage leaders and/or senior professionals, strengthen role clarity, decision quality, accountability, empowerment, career development, and succession planning.

• Own or provide senior-level input into resource planning, budget planning, vendor proposal review, staffing strategy, outsourcing strategy, and timeline planning for the CDM function or assigned portfolio

• Monitor industry trends, technologies, data standards, outsourcing models, and evolving regulatory expectations related to CDM; identify and lead strategic process, sys

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