Global Medical Affairs Lead, Oncology

About this role

The Role

This role can be based in either our Cambridge, MA, or Princeton, NJ office

Joining Moderna offers the unique opportunity to be part of a pioneering team that's revolutionizing medicine through mRNA technology, with a diverse pipeline of development programs across various diseases.

As an employee, you'll be part of a continually growing organization, working alongside exceptional colleagues and strategic partners worldwide, contributing to global health initiatives.

Moderna's commitment to advancing the technological frontier of mRNA medicines ensures a challenging and rewarding career experience, with the potential to make a significant impact on patients' lives worldwide.

Moderna is seeking a Global Medical Lead to lead medical affairs strategy across our Oncology portfolio, spanning early development through commercialization. This role offers a unique opportunity to influence the direction of mRNA oncology programs from a scientific and strategic perspective, with a strong emphasis on external engagement, data generation, and cross-functional alignment. As a key member of the global Medical Affairs team, you will be responsible for integrated evidence planning, medical governance leadership, and driving scientific thought leadership worldwide. The role will interface extensively with regulatory, clinical, commercial, and external stakeholders to ensure the success of Moderna’s oncology assets. This is a high-impact position suited for a strategic thinker, scientific storyteller, and matrix leader with a passion for innovation in oncology. The successful candidate will report to the VP, Head of Medical Affairs Oncology.

Here’s What You’ll Do Your key responsibilities will be: • Owning and leading the global medical strategy across Moderna’s oncology portfolio, ensuring seamless integration from early development to lifecycle management.

• Serving as final medical accountability for assigned oncology programs, including delivery of the integrated medical plan.

• Driving medical leadership in governance bodies and cross-functional decision-making forums, ensuring alignment between development, regulatory, and commercial functions.

• Leading the Development Integrated Evidence Team to build comprehensive data packages for regulators, payers, and other stakeholders.

• Acting as global medical lead in interactions with health authorities and payers, providing strategic input and medical representation.

Your responsibilities will also include: • Directing a cross-functional global medical matrix team (Scientific Communications, Field Medical, Patient Advocacy), ensuring timely execution of deliverables.

• Leading global launch readiness for oncology assets, including medical training, evidence generation, scientific engagement, and narrative development.

• Building partnerships with global, regional, and national thought leaders to shape best practices and influence health policy.

• Developing and executing publication strategies, medical education initiatives, and real-world evidence programs to strengthen knowledge exchange.

• Managing medical affairs budget and resource planning for assigned programs, aligning with broader franchise objectives.

• Partnering with the VP, Oncology and cross-functional stakeholders to shape the long-term medical direction and investment strategy for the franchise.

The key Moderna Mindsets you’ll need to succeed in the role: • We behave like owners. The solutions we’re building go beyond any job description. In this highly autonomous role, you will take full ownership of the medical strategy for Moderna’s oncology assets, driving high-quality execution and accountability across complex cross-functional landscapes.

• We digitize everywhere possible using the power of code to maximize our impact on patients. This role offers the opportunity to engage with Moderna’s digitally integrated ecosystem and leverage AI-powered data tools to support evidence generation, decision-making, and medical excellence.

Here’s What You’ll Need (Basic Qualifications) • MD or non-US equivalent, PharmD, or PhD with extensive oncology medical affairs leadership experience

• Minimum of 15 years of experience in Medical Affairs, with a strong track record in global roles.

• Demonstrated leadership of global launch planning and execution in oncology or immuno-oncology settings.

• Deep expertise in oncology therapeutic area required

• Strong strategic thinking and leadership skills in a global medical affairs role.

• Experience in regulatory, scientific communication, and external stakeholder engagement.

• Launch experience global and/or locally

Here’s What You’ll Bring to the Table (Preferred Qualifications) • melanoma and immunotherapy experience preferred.

• Strong track record of KOL engagement, scientific communication, and external representation

• Experience navigating strategic external collaborations and cross-company governance

• Expertise in cross-functional team leadership, including pharmacovigilance, biostatistics, clinical operations, and regulatory affairs

• Strategic and operational mindset with excellent project leadership capabilities

• Comfort managing cross-functional deliverables and owning timelines and outputs at a program level.

• Exceptional communication skills with the ability to translate complex science into clear, impactful messaging

• Ability to thrive in a fast-paced environment, balancing strategic leadership with hands-on execution

• A desire to make an impact as part of a high-growth, transformational company that is Bold, Relentless, Curious, and Collaborative.

Pay & Benefits At Moderna, we believe that when you feel your best, you can do your best work. That’s why our benefits and well-being resources are designed to support you—at work, at home, and everywhere in between. • Competitive healthcare, plus voluntary benefit programs to support your unique needs • A holistic approach to well-being, with acces

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