Director, Direct-to-Patient Operations – MariTide

About this role

Career Category Marketing Job Description Join Amgen’s Mission of Serving Patients

At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do.

Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives.

Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career.

Amgen is now preparing to enter the obesity market. Its lead candidate, MariTide, is in Phase 3 development and has shown competitive weight-loss efficacy, a strong safety profile, and a convenient dosing interval. The Phase 3 MARITIME program is studying MariTide in obesity and overweight and in obesity-related conditions—including type 2 diabetes, heart failure, obstructive sleep apnea, and atherosclerotic cardiovascular disease—alongside a broader pipeline of oral and injectable, incretin and non-incretin approaches. To move with speed, Amgen has stood up a dedicated organization focused on obesity and related conditions. Headquartered in Thousand Oaks, California, Amgen employs roughly 31,500 people worldwide and reported $36.8 billion in total revenue in 2025.

Director, Direct-to-Patient Operations – MariTide

This role will support the U.S. launch of MariTide, Amgen is building a Direct-to-Patient (DTP) channel that operates alongside traditional access pathways. The model combines digital intake, telehealth-enabled care, and end-to-end fulfillment into a single, integrated experience that routes patients across cash-pay and reimbursed options based on their needs and coverage.

Reporting to the Executive Director, US Direct-to-Patient Lead, the Director, DTP Operations will own the day-to-day operational infrastructure that keeps the DTP channel running, at launch and at scale. Where the Director, DTP Channel Strategy and Partnerships defines how the channel is designed and who the partners are, this role ensures the channel actually works: intake flows, telehealth and fulfillment integration, billing and payment execution, patient support programs, and the operational systems and processes that tie it all together.

The Director will lead a team of three Sr. Managers covering cash and coupon programs, copay support, and intake/benefits/prior auth programs, with potential for additional hires over time. This is an operations leadership role that requires equal command of process design and improvement, systems integration, people leadership, and performance management, working in a high-visibility, fast-moving launch environment where patient-facing reliability is non-negotiable.

Key Activities and Accountabilities

• DTP Operational Model & Systems • Own the operational infrastructure of the DTP channel, including core workflows, intake routing, fulfillment execution, billing, and patient support systems

• Translate the DTP channel architecture and system design set by the ED into operational processes, SOPs, and team-level execution plans

• Partner with the Director, DTP Channel Strategy and Partnerships to ensure channel design decisions are operationally viable and launch-ready

• Ensure operational readiness across all systems and processes ahead of launch, including end-to-end testing and contingency planning

• Drive continuous improvement post-launch, identifying operational friction and leading structured problem-solving to resolution

• Cash, Coupon & Copay Programs • Oversee the design, build, and operational management of cash-pay, coupon, and copay support programs within the DTP channel

• Ensure payment workflows are accurately implemented, tested, and reconciled across cash-pay and reimbursed pathways

• Partner with Value & Access and Contracts & Pricing on program economics, eligibility logic, and Gross-to-Net implications

• Lead the Sr. Managers for Cash/Coupon Programs and Copay Support in delivering operationally sound, patient-friendly payment experiences

• Intake, Benefits Verification & Prior Authorization • Own the operational design and execution of intake workflows, benefits verification, and prior authorization processes within the DTP channel

• Ensure intake routing logic correctly identifies patient coverage and directs patients to the appropriate pathway with minimal friction

• Partner with payer, hub, and/or fulfillment partners on prior auth workflows, approval rates, and appeal processes

• Lead the Sr. Manager, Intake/Benefits/Prior Auth Programs in managing day-to-day intake operations and continuous improvement

• Performance Management & Operational Governance • Define and own operational KPIs across the DTP channel, including intake completion rates, fulfillment SLAs, prior auth approval rates, copay utilization, and patient drop-off

• Partner with Commercial Data & Analytics (CD&A) to build dashboards and reporting that give leadership real-time visibility into operational health

• Establish governance cadences across the operations team and with operational partners, ensuring issues are surfaced and resolved quickly

• Drive accountability to SLAs across internal teams and external partners; escalate material gaps with clear resolution plans

• Cross-Functional Collaboration • Partner closely wit

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