Data Management TA Lead, Early Development

About this role

A healthier future. It’s what drives us to innovate. To continuously advance science and ensure everyone has access to the healthcare they need today and for generations to come. Creating a world where we all have more time with the people we love. That’s what makes us Roche.

This role is in Early Development Biometrics (EDB), a core function within Product Development Data Sciences (PDD) that provides strategic leadership and scientific rigor across early clinical development at Roche. We partner across Biostatistics, Analytical Data Science, and Data Management to enable data-driven decision-making from first-in-human through proof-of-concept studies.

As trusted partners in early development, we design efficient and innovative clinical trials, apply rigorous statistical methods, and implement high-quality programming and analytical solutions to accelerate timelines, de-risk development, and increase the probability of technical success. Our integrated teams operate with agility and scientific depth, supporting exploratory analyses, early regulatory engagements, and complex data-generation needs across therapeutic areas. Together, we bring scientific rigor, technical innovation, and strategic insight to shape the future of early development and deliver better outcomes for patients.

Early Development Biometrics is also home to Methods Collaboration & Outreach (MCO), which enables the most impactful use of quantitative methodology across PDD through internal consultation, external collaboration, and continuous capability building; and Visual Analytics, which creates and maintains interactive dashboards that drive high-quality Medical Data Review (MDR) and safety signal detection, aligned with Risk-Based Quality Management (RBQM) principles and Critical-to-Quality (CtQ) endpoints.   The Opportunity:  The Data Management TA Lead in Early Development Biometrics is accountable for setting and executing the data management strategy across a therapeutic area (TA), ensuring high-quality, reliable, and analysis-ready data in support of early-phase clinical development. This role directly leads a team of Data Managers responsible for ensuring data quality, integrity, and readiness across multiple studies, partnering closely with Biostatistics, Data Science, Clinical Operations, and vendor teams. It provides technical leadership across multiple programs, enabling consistent, scalable, and scientifically aligned data practices tailored to the unique demands of early research. As a key leader within the Early Development Biometrics function, the TA Lead anticipates and navigates complexities such as evolving endpoints, exploratory data types, and limited standardization, driving fit-for-purpose solutions that support decision-making under uncertainty. This includes aligning data strategies with early clinical development goals and ensuring biometrics deliverables are both scientifically rigorous and operationally feasible. With deep subject matter expertise and a strong understanding of the data lifecycle, the TA Lead also contributes to process optimization, standards evolution, and innovation across early development programs. This role also drives continuous improvement, talent development, and a culture of accountability, collaboration, and innovation within the data management team.

You will lead a diverse team of 6-8 data managers, and will also have overall responsibility for a early development program area . Your primary responsibilities will be in service to your direct reports, and to the molecule or disease area team you are supporting. You will help match talent to opportunities by understanding the skills and aspirations of your team and understanding the PDD strategic context and possible opportunities. You will coach and mentor through your extensive data management experience and drug development expertise. Additionally, you will establish and foster key internal and external relationships, purposefully collaborating to be at the forefront of our industry. • You provide strategic leadership for data management across a therapeutic area in early development, ensuring data strategies align with scientific objectives and evolving program needs

• You design and drive implementation of fit-for-purpose data practices that support flexible study designs, exploratory endpoints, and rapid iteration

• You anticipate and solve complex challenges involving non-standard data, external data sources, and limited precedent, ensuring readiness for internal and downstream decision-making

• You lead alignment across biometrics contributors (e.g., data standards, statistical programming) to ensure consistency, efficiency, and data reusability across early-phase programs

• You represent Early Development Data Management in internal forums focused on functional excellence, capability development, and process innovation

• You set quality expectations and provide expert guidance across studies, serving as a senior advisor and mentor to study-level data managers and other data contributors

• You lead and develop a team of Data Managers supporting multiple studies across one or more molecules within a subset of a disease area

• You set clear goals, development plans, and performance expectations to enable functional growth and delivery

• You manage team workload, capacity planning, and study allocation based on program complexity and milestones

• You foster collaboration and information sharing across study teams and with cross-functional partners

• You represent data management in molecule-level or DA-level forums and ensure alignment with clinical and data science strategies

• You role-model effective leadership behaviors and coach team members to grow technical, leadership, and strategic skills

• You serve as a role model in demonstrating Roche’s Leadership Commitments and the Pharma Operating Principles

• You work with other DM TA Leads and People Leaders within Early Development Biometri

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