Bioinformatics Scientist

About this role

Job Family : Scientist Travel Required : None Clearance Required : Ability to Obtain Public Trust

What You Will Do:

We are looking for a Bioinformatics Scientist to support the operational objectives of the National Institute of Environmental Health Sciences (NIEHS) through advanced genomic data analysis, bioinformatics programming, and computational biology support. This position is a full-time position located in Research Triangle Park, NC and is telework eligible.

Analyze NGS, GWAS, genomic, biological, epidemiology, and population-based datasets, including ChIP-Seq, RNA-Seq, miRNA-Seq, SNP/structural variation discovery, imputation, stratification, haplotype, pathway, principal component, meta-analysis, and related statistical analyses.

• Interpret genomic and targeted population study data, associated metadata, gene expression, exon, tiling, promoter, microarray, and multi-platform results to extract biologically meaningful insights.

• Develop, implement, deploy, and maintain bioinformatics workflows, custom programs, utility scripts, macros, algorithms, analytical tools, and computational processes supporting experimental design, quality analysis, genome/metagenome integration, and biological discovery.

• Use commercial software, freeware, custom-developed solutions, and high-performance computing environments to support scientific objectives, maintain workstations, and identify relevant analytical software solutions.

• Collaborate with biologists, statisticians, bioinformaticians, investigators, and research teams to design analytical models, support data collection and experimental activities, and participate in scientific programming, laboratory, and interdisciplinary meetings.

• Prepare reports, protocols, technical documentation, publication-quality graphics, and deliverables supporting NGS analyses, GWAS studies, statistical analyses, workflow development, publications, training activities, and scientific presentations.

• Present findings to investigators, bioinformatics teams, study groups, and external audiences, and develop and deliver bioinformatics training materials, presentations, tutorials, and short-course instruction.

What You Will Need:

• Master's degree in Bioinformatics, Biostatistics, Computational Biology, Biological Sciences, Mathematics, Computer Science, Environmental Science, Microbiology, Molecular Biology, or related scientific discipline.

• Minimum of FIVE (5) years of experience in bioinformatics, computational biology, biostatistics, genomics, or a related field.

• Hands-on background analyzing next-generation sequencing data and genomic datasets.

• Working knowledge of Genome-Wide Association Studies (GWAS).

• Background performing bulk RNA sequencing analysis.

• Skilled in conducting microbiome, phylogenetic, multi-omics, microarray, and cluster analyses.

• Ability to work with large and complex biological datasets.

• Proven ability to develop bioinformatics pipelines and analytical workflows.

• Proficiency with R, Python, MATLAB, Perl, Shell scripting, Unix/Linux environments, and Java.

• Demonstrated ability to collaborate with multidisciplinary scientific teams.

• Ability to prepare technical reports, scientific documentation, and publication-quality visualizations.

• Must be able to obtain and maintain a Federal or DoD “public trust”; candidates must receive approved adjudication prior to onboarding with Guidehouse. Candidates with an active public trust or suitability are preferred.

What Would Be Nice To Have:

• Ph.D. in Bioinformatics, Biostatistics, Computational Biology, Biological Sciences, or a related scientific discipline.

• Background supporting federal biomedical or environmental health research programs.

• Strong written and verbal communication skills, including presentation experience.

• Ability to develop custom bioinformatics applications and advanced computational algorithms.

• Familiarity supporting high-performance computing environments.

• Ability to provide bioinformatics training, mentoring, and instructional support.

• Demonstrated contributions to scientific manuscripts and peer-reviewed publications.

• Collaboration across interdisciplinary genomic, epidemiologic, and population-based research programs.

What We Offer: Guidehouse offers a comprehensive, total rewards package that includes competitive compensation and a flexible benefits package that reflects our commitment to creating a diverse and supportive workplace.

Benefits include: • Medical, Rx, Dental & Vision Insurance

• Personal and Family Sick Time & Company Paid Holidays

• Parental Leave

• 401(k) Retirement Plan

• Group Term Life and Travel Assistance

• Voluntary Life and AD&D Insurance

• Health Savings Account, Health Care & Dependent Care Flexible Spending Accounts

• Transit and Parking Commuter Benefits

• Short-Term & Long-Term Disability

• Tuition Reimbursement, Personal Development, Certifications & Learning Opportunities

• Employee Referral Program

• Corporate Sponsored Events & Community Outreach

• Care.com annual membership

• Employee Assistance Program

• Supplemental Benefits via Corestream (Critical Care, Hospital Indemnity, Accident Insurance, Legal Assistance and ID theft protection, etc.)

• Position may be eligible for a discretionary variable incentive bonus

About Guidehouse Guidehouse is an Equal Opportunity Employer–Protected Veterans, Individuals with Disabilities or any other basis protected by law, ordinance, or regulation.

Guidehouse will consider for employment qualified applicants with criminal histories in a manner consistent with the requirements of applicable law or ordinance including the Fair Chance Ordinance of Los Angeles and San Francisco.

If you have visited our website for information about employment opportunities, or to apply for a position, and you require an accommodation, please contact Guidehouse Recruiting at 1-571-633-1711 or via email at RecruitingAccommodation@guidehouse

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